Prevalence and risk factors of latent tuberculosis infection in hemodialysis patients in Southwest Iran
Więcej
Ukryj
1
School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran
2
School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3
Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Science, Shiraz, Iran
4
College of Agricultural Sciences, Shiraz Branch, Islamic Azad University, Shiraz, Iran
5
Infectious Disease, Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran
Data nadesłania: 02-12-2023
Data akceptacji: 06-03-2024
Data publikacji online: 17-04-2024
Data publikacji: 07-06-2024
Autor do korespondencji
Gordafarin Nikbakht
Social Determinants of Health Research Center, Yasuj University of Medical Sciences, Yasuj, Iran.
Przegl Epidemiol 2024;78(1):22-26
SŁOWA KLUCZOWE
STRESZCZENIE
INTRODUCTION. Tuberculosis (TB) is a significant global health concern, particularly in developing countries. Diagnosing latent tuberculosis infection (LTBI) in hemodialysis patients is crucial because of the risk of developing active tuberculosis in this population due to attenuated immune response. Herein, we assessed the prevalence of LTBI in hemodialysis patients.
METHODS. In this cross-sectional study, we included all patients referred to hemodialysis centers in Kohgiluyeh and Boyer-Ahmad Province, southwest Iran, in 2018 through census sampling. Tuberculin skin test (TST) was utilized to screen the patients for LTBI. All steps were done by trained physicians.
RESULTS. In total, 183 patients (mean age: 59.3, SD= 16.0) were included in the study of which 76 (41.5%) were females, and 107 (58.5%) were males. Neither the patients nor their family members had a history of tuberculosis. Assuming an above 5-millimeter enduration as a positive TST result, 22 patients (12%) had LTBI. None of the demographic or clinical features differed between TST -negative and -positive groups.
CONCLUSION. Hemodialysis patients are prone to LTBI due to several immunological and environmental factors. Screening for LTBI may be beneficial to prevent active tuberculosis in this population.